BeOne Medicines Ltd.
06160
2025930
13.09
571XIVA
2025930
2025930
20252025
2025116
1995(Private Securities LitigationReform Act of 1995)
BCL2
10-Q
2025
2025116
Olivier BrandicourtMargaret Han DuganMichael GollerAnthony C. HooperRanjeev KrishanaAlessandro RivaCorazon (Corsee) D. SandersShalini Sharp
2025?20251441%?
?
1051%?(GAAP)(ADS)1.09GAAPADS2.65
?47(ASH)
ONC061606882352025
?
BTKBTK
BCL2BTK CDAC BGB-16673(CLL)B
93093020252024(%)20252024(%)$ 1,395,013$ 993,44740%$ 3,805,619$ 2,661,51143%$ 17,271$ 8,152112%$ 39,244$ 20,90688%$ 1,412,284$ 1,001,59941%$ 3,844,863$ 2,682,41743%GAAP$ 163,114$ (120,265)236%$ 262,101$ (488,774)154%
*$ 341,184$ 65,630420%$ 755,486$ (33,247)2,372%GAAP$ 124,841$ (121,350)203%$ 220,431$ (492,905)145%
*$ 303,663$ 51,582489%$ 692,622$ (71,020)1,075%GAAPADS$ 1.13$ (1.15)198%$ 2.03$ (4.71)143%
ADS*$ 2.76$ 0.49463%$ 6.38$ (0.68)1,038%GAAPADS$ 1.09$ (1.15)195%$ 1.96$ (4.71)142%
ADS*$ 2.65$ 0.48452%$ 6.14$ (0.68)1,003%*$ 354,469$ 54,714548 %$ 561,916$ (615,974)191%
* GAAP
GAAPGAAP
2025
20251410
?2025149.93
?
7.435.04?
?
?20257.3947%
?
BTK
?20251.6368%
?
?20251.9117%2025GAAP85.9%
82.8%
???202586.3%
84.9%
2025
GAAPGAAP20252024
(%)
20252024
(%)$ 523,662$ 496,1796%$ 445,904$ 405,54510%$ 528,998$ 455,22316%$ 434,484$ 380,73714%$ 1,052,660$ 951,40211%$ 880,388$ 786,28212%
202593020249309
GAAPGAAP20252024
(%)
20252024
(%)$ 1,530,445$ 1,411,2838%$ 1,311,156$ 1,193,49410%$ 1,526,199$ 1,326,37915%$ 1,271,650$ 1,116,80514%$ 3,056,644$ 2,737,66212%$ 2,582,806$ 2,310,29912%2025GAAP2025
20500(SG&A)2025GAAPSG&A2025SG&A38%46%
GAAPGAAP2025GAAP1.252.46
20250.090.08
ADS1.131.090.09
ADS1.1520253.543
2025
202510-Q
2025
2025
2025
2025
50535153GAAP
41444143GAAP%80%90%GAAP
20259
20255153
?
202480%90%GAAP
GAAPGAAP
?
? 7557? (EC)
?? 4716? EC
(NSCLC)
?
? (GC)3? GC
? BCL2
o (FDA)
(R/R)(MCL)o R/R(WM)2
? BGB-16673 (BTK CDAC):
o BTKR/R CLL
? BC-C9074(B7-H4 ADC)
? BG-58067MTAPRMT5? (AMG 757)3
? BGB-B2033GPC3×41BB
? BGB-45035 (IRAK4 CDAC):
oo 2? BGB-166731b
?
? (MZL)2026
?
? 2026? BCL2
o
?
+(AV)3
2026
o 32026? BGB-16673 (BTK CDAC):
o R/R CLL2026
? BGB-43395CDK4
HRHER2
2026
? HER2
Zymeworks/Jazz
HER23(Herizon GEA-301)
2025
? BGB-45035 (IRAK4 CDAC):
o 22026
? Royalty Pharma
IMDELLTRA
?
tarlatamab
9.5
? Pharmacyclics
Pharmacyclics
?
11,672,803Pharmacyclics
20251168202511692025
(www.beonemedicines.com.cn )
12,000 www.beonemedicines.com.cn
1995(Private Securities LitigationReform Act of 1995)
BCL2
10-Q
+86 10 5895 8058+86 21 3159 1070ir@ beonemed.com media@ beonemed.com
(ADS)ADS
9309302025202420252024
$ 1,395,013$ 993,447$ 3,805,619$ 2,661,511 17,2718,15239,24420,906 1,412,2841,001,5993,844,8632,682,417 196,510170,462526,118433,529
1,215,774831,1373,318,7452,248,888 523,662496,1791,530,4451,411,283 528,998455,2231,526,1991,326,379 1,052,660951,4023,056,6442,737,662
163,114(120,265)262,101(488,774) 3,02910,64312,37440,028 (18,979)11,318(6,862)1,096
147,164(98,304)267,613(447,650)
22,32323,04647,18245,255$ 124,841$ (121,350)220,431(492,905)
$ 0.09$ (0.09)0.16(0.36) $ 0.08$ (0.09)0.15(0.36)
1,432,801,6991,376,751,8731,410,497,0621,361,216,7631,488,750,3541,376,751,8731,465,535,0041,361,216,763ADS $ 1.13$ (1.15)2.03(4.71) $ 1.09$ (1.15)1.96(4.71)
ADS110,215,515105,903,990108,499,774104,708,982ADS114,519,258105,903,990112,733,462104,708,982
930123120252024
$ 4,110,542$ 2,638,747
863,281676,278531,687494,9861,628,1141,578,4237,632,5865,920,910
383,676404,9971,001,661803,713885,00090,596165,440952,8671,018,0133,503,2602,588,688$ 4,129,326$ 3,332,222
9309302025202420252024
$ 2,786,086$ 2,617,931$ 2,638,747$ 3,185,984 402,553188,369710,233(215,791) (49,274)(133,882)(237,820)(454,745) 961,27212,662962,520197,972 9,90528,34836,8628
1,324,45695,4971,471,795(472,556)
$ 4,110,542$ 2,713,428$ 4,110,542$ 2,713,428
(Non-GAAP)GAAP
GAAPGAAPGAAP
GAAP
GAAPGAAPGAAP
GAAP
GAAP
GAAPGAAP
GAAPGAAP
GAAPGAAPGAAPGAAPGAAP
GAAPGAAP
9309302025202420252024GAAPGAAP$ 196,510$ 170,462$ 526,118$ 433,529
4,26119,58910,19524,618
1,5371,1868,4593,546
$ 190,712$ 149,687$ 506,571$ 405,365GAAPGAAP$ 523,662$ 496,179$ 1,530,445$ 1,411,283
58,83947,670164,998141,12118,91942,96454,29176,668
$ 445,904$ 405,545$ 1,311,156$ 1,193,494GAAPGAAP$ 528,998$ 455,223$ 1,526,199$ 1,326,379
81,94766,933221,792192,89012,5507,47532,71216,60617784578
$ 434,484$ 380,737$ 1,271,650$ 1,116,805GAAPGAAP$ 1,052,660$ 951,402$ 3,056,644$ 2,737,662
140,786114,603386,790334,01131,46950,43987,00393,27417784578
$ 880,388$ 786,282$ 2,582,806$ 2,310,299
9309302025202420252024GAAPGAAP$ 163,114$ (120,265)$ 262,101$ (488,774)
140,786114,603386,790334,01135,73070,02897,198117,892
1,5541,2648,5043,624
$ 341,184$ 65,630$ 755,486$ (33,247)GAAPGAAP$ 124,841$ (121,350)$ 220,431$ (492,905)
140,786114,603386,790334,011
35,73070,02897,198117,892
1,5541,2648,5043,624
18,72234,216
(926)962(9,663)3,365GAAP
(17,044)(13,925)(45,747)(37,007)$ 303,663$ 51,582$ 692,622$ (71,020)GAAPGAAP$ 0.09$ (0.09)$ 0.16$ (0.36)
0.100.080.270.25
0.020.050.070.09
0.000.000.010.00
0.000.000.000.00
0.010.000.020.00(0.00)0.00(0.01)0.00GAAP
(0.01)(0.01)(0.03)(0.03)$ 0.21$ 0.04$ 0.49$ (0.05)
9309302025202420252024GAAPGAAP$ 0.08$ (0.09)$ 0.15$ (0.36)
0.090.080.260.25
0.020.050.070.09
0.000.000.010.00
0.000.000.000.00
0.010.000.020.00
(0.00)0.00(0.01)0.00GAAP
(0.01)(0.01)(0.03)(0.03)$ 0.20$ 0.04$ 0.47$ (0.05)GAAPADS
GAAPADS$ 1.13$ (1.15)$ 2.03$ (4.71)
1.281.083.563.19
0.320.660.901.13
0.010.010.080.03
0.000.000.010.00
0.170.000.320.00
(0.01)0.01(0.09)0.03GAAP
(0.15)(0.13)(0.42)(0.35)ADS$ 2.76$ 0.49$ 6.38$ (0.68)
9309302025202420252024GAAPADS
GAAPADS
$ 1.09$ (1.12)$ 1.96$ (4.71)
1.231.063.433.19
0.310.650.861.13
0.010.010.080.03
0.000.000.010.00
0.160.000.300.00
(0.01)0.01(0.09)0.03GAAP
(0.15)(0.13)(0.41)(0.35)ADS$ 2.65$ 0.48$ 6.14$ (0.68)
1. GAAP
2. 2024GAAPADSADS
ADS0.03GAAPGAAP
9309302025202420252024GAAP
(GAAP)$ 402,553$ 188,369$ 710,233$ (215,791)
(48,084)(133,655)(148,317)(400,183)GAAP$ 354,469$ 54,714$ 561,916$ (615,974)